publications
John A, Smith, ES, Jones, DS, Soyars, CL Nimchuk, ZL. A network of CLAVATA receptors buffers auxin-dependent meristem maintenance. Nature Plants 2023 August. https://doi.org/10.1038/s41477-023-01485-y
DeFalco TA, Anne P, James SR, Willoughby A, Johanndrees O, Genolet Y, Anne-Marie Pullen A-M,, Zipfel C, Hardtke CS, Nimchuk ZL. A conserved regulatory module regulates receptor kinase signaling in immunity and development. Nat. Plants 8, 356–365 (2022). DOI: 10.1038/s41477-022-01134-w
Stegmann M, Zecua-Ramirez P, Ludwig C, Lee HS, Peterson B, Nimchuk ZL, Belkhadir Y, Hückelhoven R. RGI-GOLVEN signaling promotes cell surface immune receptor abundance to regulate plant immunity. Online ahead of print. EMBO Rep 2022 Mar 1;e53281. doi: 10.15252/embr.202153281.
Crook AD, Willoughby AC, Hazak O, Okuda S, VanDerMolen KR, Soyars CL, Cattaneo P, Clark NM, Sozzani R, Hothorn M, Hardtke CS, Nimchuk ZL. BAM1/2 receptor kinase signaling drives CLE peptide-mediated formative cell divisions in Arabidopsis roots. Proc Natl Acad Sci U S A. Dec 2020, 202018565; DOI: 10.1073/pnas.2018565117
Jones DS, John A, VanDerMolen KR, Nimchuk ZL. CLAVATA Signaling Ensures Reproductive Development in Plants across Thermal Environments. Current Biology. 2020 November 5. DOI:https://doi.org/10.1016/j.cub.2020.10.008
Marquès-Bueno MM, Armengot L, Noack LC, Bareille J, Rodriguez L, Platre MP, Bayle V, Liu M, Opdenacker D, Vanneste S, Möller BK, Nimchuk ZL, Beeckman T, Caño-Delgado AI, Friml J, Jaillais Y. Auxin-Regulated Reversible Inhibition of TMK1 Signaling by MAKR2 Modulates the Dynamics of Root Gravitropism
Current Biology. 2020 November 5. DOI:https://doi.org/10.1016/j.cub.2020.10.011
Burr CA, Sun J, Yamburenko MV, Willoughby A, Hodgens C, Boeshore SL, Elmore A, Atkinson J, Nimchuk ZL, Bishopp A, Schaller GE, Kieber JJ. The HK5 and HK6 cytokinin receptors mediate diverse developmental pathways in rice. Development. 2020 Oct 27. doi: 10.1242/dev.191734.
Fernandez AI, Vangheluwe N, Xu K, Jourquin J, Claus LAN, Morales-Herrera S, Parizot B, De Gernier H, Yu Q, Drozdzecki A, Maruta T, Hoogewijs K, Vannecke W, Peterson B, Opdenacker D, Madder A, Nimchuk ZL, Russinova E, Beeckman T. GOLVEN peptide signaling through RGI receptors and MPK6 restricts asymmetric cell division during lateral root initiation. Nature Plants. 2020 May. doi: 10.1038/s41477-020-0645-z.
Smit M, McGregor S, Sun H, Gough C, Bågman AM, Soyars CL, Kroon JT, Gaudinier A, Williams CJ, Yang X, Nimchuk ZL, Weijers D, Turner SR, Brady SM, Etchells O. A PXY-Mediated Transcriptional Network Integrates Signaling Mechanisms to Control Vascular Development in Arabidopsis. Plant Cell 2019 December. https://doi.org/10.1105/tpc.19.00562
Worthen JM, Yamburenko MV, Lim J, Nimchuk ZL, Kieber JJ, Schaller GE. Type-B response regulators of rice play key roles in growth, development and cytokinin signaling. Development. 2019 Jul 10 . https://doi.org/10.1242/dev.174870
Rodriguez-Leal D, Xu C, Kwon CT, Soyars C, Demesa-Arevalo E, Man J, Liu L, Lemmon ZH, Jones DS, Van Eck J, Jackson DP, Bartlett ME, Nimchuk ZL, Lippman ZB. Evolution of buffering in a genetic circuit controlling plant stem cell proliferation. Nature Genetics 2019 May. https://doi.org/10.1038/s41588-019-0389-8
Vatén A, Soyars CL, Tarr PT, Nimchuk ZL, Bergmann DC. Modulation of Asymmetric Division Diversity through Cytokinin and SPEECHLESS Regulatory Interactions in the Arabidopsis Stomatal Lineage. Developmental Cell. 2018 Oct 8. https://doi.org/10.1016/j.devcel.2018.08.007
Whitewoods CD, Cammarata J, Venza ZN, Sang S, Crook AD, Aoyama T, Wang XY, Waller M, Kamisugi Y, Cuming AC, Szövényi P, Nimchuk ZL, Roeder AHK, Scanlon MJ, Harrison CJ. CLAVATA Was a Genetic Novelty for the Morphological Innovation of 3D Growth in Land Plants. Current Biology, 19 July 2018. https://doi.org/10.1016/j.cub.2018.05.068
Soyars, CL , Peterson, BA, Burr, CA, Nimchuk, ZL. Cutting Edge Genetics: CRISPR/Cas9 Editing of Plant Genomes. Plant and Cell Physiology, 18 April 2018 https://doi.org/10.1093/pcp/pcy079
Liu, H, Soyars, CL, Li, J, Fei, Q, He, G, Peterson, BA, Meyers, BC, Nimchuk, ZL, Wang, X. CRISPR/Cas9-mediated resistance to cauliflower mosaic virus. Plant Direct 2018 March 7. http://onlinelibrary.wiley.com/doi/10.1002/pld3.47
Moody, LA, Kelly, S, Coudert, Y, Nimchuk, ZL, Harrison, CJ, Langdale, JA. Somatic hybridization provides segregating populations for the identification of causative mutations in sterile mutants of the moss Physcomitrella patens. New Phytologist 2018 March 2. http://onlinelibrary.wiley.com/doi/10.1111/nph.15069
Hodgens, C, Nimchuk, ZL, Kieber, JJ. indCAPS: A tool for designing screening primers for CRISPR/Cas9 mutagenesis events. PLOS One. 2017 November 15. https://doi.org/10.1371/journal.pone.0188406
Moussu, SA, Doll, NM, Chamot, S, Brocard, L, Creff, A, Fourquin, C, Widiez, T, Nimchuk, ZL, Ingram, GC. ZHOUPI and KERBEROS Mediate Embryo/Endosperm Separation by Promoting the Formation of an Extra-Cuticular Sheath at the Embryo Surface. The Plant Cell July 2017. DOI: https://doi.org/10.1105/tpc.17.00016
Denbow CJ, Lapins S, Dietz N, Scherer R, Nimchuk ZL, Okumoto S. Gateway-compatible CRISPR-Cas9 vectors and a rapid detection by high-resolution melting curve analysis. (2017) Frontiers in Plant Sciences. https://doi.org/10.3389/fpls.2017.01171
Nimchuk, ZL, Perdue, TD. Live Imaging of Shoot Meristems on an Inverted Confocal Microscope Using an Objective Lens Inverter Attachment.
Front. Plant Sci. 2017 May 19. doi: https://doi.org/10.3389/fpls.2017.00773
Nimchuk ZL. CLAVATA1 controls distinct signaling outputs that buffer shoot stem cell proliferation through a two-step transcriptional compensation loop. PLOS Genetics. 2017 Mar 29. doi: http://dx.doi.org/10.1371/journal.pgen.1006681
Nishimura MT, Anderson RG, Cherkis KA, Law TF, Liu QL, Machius M, Nimchuk ZL, Yang L, Chung EH, El Kasmi F, Hyunh M, Osborne Nishimura E, Sondek JE, Dangl JL (2017) TIR-only protein RBA1 recognizes a pathogen effector to regulate cell death in Arabidopsis. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10) DOI: 10.1073/pnas.1620973114
Liu Y, Miao J, Traore S, Kong D, Liu Y, Zhang X, Nimchuk ZL, Liu Z, Zhao B (2016). SacB-SacR gene cassette as the negative selection marker to suppress Agrobacterium overgrowth in Agrobacterium-mediated plant transformation. Frontiers in Molecular Biosciences. 26 October 2016 http://dx.doi.org/10.3389/fmolb.2016.00070
Peterson BA, Haak DC, Nishimura MT, Teixeira PJPL, James SR, Dangl JL, Nimchuk ZL. (2016) Genome-Wide Assessment of Efficiency and Specificity in CRISPR/Cas9 Mediated Multiple Site Targeting in Arabidopsis. PLOS One 11(9): e0162169.doi:10.1371/ journal.pone.0162169.
Soyars CL, James SR, Nimchuk ZL. Ready, aim, shoot: stem cell regulation of the shoot apical meristem. Curr Opin Plant Biol. (2016) Jan 21;29:163-168. https://dx.doi.org/10.1016/j.pbi.2015.12.002
Nimchuk ZL, Zhou Y, Tarr PT, Peterson, BA, and Meyerowitz EM. Plant stem cell maintenance by transcriptional cross regulation of related receptor kinases. Development. (2015) 142: 1043-1049. https://dx.doi.org/10.1242/dev.119677
Zhou Y, Liu X, Engstrom EM, Nimchuk ZL, Pruneda-Paz J, Tarr PT, Yan A, Kay SA, Meyerowitz EM. Dual control of plant stem cell production by conserved interactions between the HAIRY MERISTEM and WUSCHEL/WUSCHEL-RELATED HOMEOBOX families of transcriptional regulators. Nature. (2015) 517:377-80. https://dx.doi.org/10.1038/nature13853
Murphy JM, Zhang Q, Young SN, Reese ML, Bailey FP, Eyers PA, Ungureanu D, Hammarén H, Silvennoinen O, Varghese LN, Chen K, Tripaydonis A, Jura N, Fukuda K, Qin J, Nimchuk Z, Mudgett MB, Elowe S, Gee CL, Liu L, Daly RJ, Manning G, Babon JJ, Lucet IS. A robust methodology to subclassify pseudokinases based on their nucleotide binding properties. Biochem J. (2014) 457, 323–334. https://dx.doi.org/10.1042/BJ20131174
Segonzac C*, Nimchuk ZL*, Beck M, Tarr PT, Robatzek S, Meyerowitz EM and Zipfel C (2011) The shoot apical meristem regulatory peptide CLV3 does not activate the immune receptor FLS2. Plant Cell 24 (8):3186-92. *Contributed equally http://dx.doi.org/10.1105/tpc.111.091264
Nimchuk ZL, Tarr PT, Meyerowitz EM. (2011). An evolutionarily conserved pseudo-kinase mediates stem cell production in plants. Plant Cell 23 (3):851-54. http://dx.doi.org/10.1105/tpc.110.075622
Nimchuk ZL, Tarr PT, Ohno C, Qu X, Meyerowitz EM. (2011). Signaling in the Arabidopsis shoot meristem stem cell niche correlates with ligand-dependent trafficking of the CLV1 receptor kinase. Current Biology 21 (5):345-52. https://dx.doi.org/10.1016%2Fj.cub.2011.01.039
Jaillais Y, Hothorn, M, Belkadir Y, Dabi T, Nimchuk ZL, Meyerowitz EM, Chory J. (2011). Tyrosine phosphorylation regulates brassinosteroid signaling at the plasma membrane. Genes and Development 25 (3):232-7. http://www.genesdev.org/cgi/doi/10.1101/gad.2001911
Previous publications on plant pathogen interactions
Ellis T*, Nimchuk Z*, Dangl JL. (2008). Arabidopsis TAO1 is a TIR-NB-LRR protein that contributes to disease resistance induced by the Pseudomonas syringae effector AvrB. PNAS 105 (17): 6475-80. *Contributed equally. https://dx.doi.org/10.1073/pnas.0802157105
Desveaux D, Singer AU, Wu A-J, McNulty BC, Musselwhite L, Nimchuk Z, Sondek J, Dangl JL. (2007). Type III effector activation via nucleotide binding, phosphorylation and host target interaction. PLOS Pathogens 3(36): e48. https://dx.doi.org/10.1371/journal.ppat.0030048
Nimchuk Z, Desveaux D, Fisher EJ, Chang JH, Dangl JL. (2007). The HopX (AvrPphE) family of Pseudomonas syringae type III effectors require a catalytic triad and a novel N-terminal domain for function. Molecular Plant Microbe Interactions 20: 346-357. https://dx.doi.org/10.1094/MPMI-20-4-0346
Belkhadir Y, Nimchuk Z, Hubert DA, Mackey D, Dangl JL. (2004) Arabidsopsis RIN4 negatively regulates RPS2 and RPM1 downstream or independent of NDR1 and is not required for AvrRpt2 or AvrRpm1 virulence functions. Plant Cell 16: 2822-35. https://dx.doi.org/10.1105/tpc.104.024117
Singer AU, Desveaux D, Betts L, Chang JH, Nimchuk Z, Grant SR, Dangl JL, Sondek J. (2004). Crystal Structure of the type III effector AvrPphF and its chaperone reveal residues required for both pathogen virulence and triggering host disease resistance. Structure 12: 1669-81. https://dx.doi.org/10.1016/j.str.2004.06.023
Nimchuk Z, Euglem T, Holt BF III, Dangl JL. (2003). Recognition and response in the plant immune system. Ann Rev Genet 37: 579-609 https://dx.doi.org/10.1146/annurev.genet.37.110801.142628
Nimchuk Z, Rohmer L, Chang JH, Dangl JL. (2001). Knowing the dancer from the dance: R-gene products and their interactions with other proteins from host and pathogen. Curr Opin Plant Biol 4: 288-94 http://dx.doi.org/10.1016/S1369-5266(00)00175-8
Nimchuk Z*, Marois E*, Kjemtrup S*, Leister RT, Katagiri F, Dangl JL. (2000). Eukaryotic fatty acylation drives plasma membrane targeting and enhances function of several type III effectors from Pseudomonas syringae. Cell 101:353-63. *Contributed equally. http://dx.doi.org/10.1016/S0092-8674(00)80846-6
Kjemtrup S, Nimchuk Z, Dangl JL. (2000). Effector proteins of phytopathogenic bacteria: bifunctional signals in virulence and host recognition. Curr Opin Microbiol 3:73-78. http://dx.doi.org/10.1016/S1369-5274(99)00054-5
Heath MC, Nimchuk ZL, Xu H. (1997). Plant nuclear migrations as indicators of critical interactions between resistant or susceptible cowpea epidermal cells and invasion hyphae of the cowpea rust fungus. New Phytol 135:689-700 http://www.jstor.org/stable/2559001
DeFalco TA, Anne P, James SR, Willoughby A, Johanndrees O, Genolet Y, Anne-Marie Pullen A-M,, Zipfel C, Hardtke CS, Nimchuk ZL. A conserved regulatory module regulates receptor kinase signaling in immunity and development. Nat. Plants 8, 356–365 (2022). DOI: 10.1038/s41477-022-01134-w
Stegmann M, Zecua-Ramirez P, Ludwig C, Lee HS, Peterson B, Nimchuk ZL, Belkhadir Y, Hückelhoven R. RGI-GOLVEN signaling promotes cell surface immune receptor abundance to regulate plant immunity. Online ahead of print. EMBO Rep 2022 Mar 1;e53281. doi: 10.15252/embr.202153281.
Crook AD, Willoughby AC, Hazak O, Okuda S, VanDerMolen KR, Soyars CL, Cattaneo P, Clark NM, Sozzani R, Hothorn M, Hardtke CS, Nimchuk ZL. BAM1/2 receptor kinase signaling drives CLE peptide-mediated formative cell divisions in Arabidopsis roots. Proc Natl Acad Sci U S A. Dec 2020, 202018565; DOI: 10.1073/pnas.2018565117
Jones DS, John A, VanDerMolen KR, Nimchuk ZL. CLAVATA Signaling Ensures Reproductive Development in Plants across Thermal Environments. Current Biology. 2020 November 5. DOI:https://doi.org/10.1016/j.cub.2020.10.008
Marquès-Bueno MM, Armengot L, Noack LC, Bareille J, Rodriguez L, Platre MP, Bayle V, Liu M, Opdenacker D, Vanneste S, Möller BK, Nimchuk ZL, Beeckman T, Caño-Delgado AI, Friml J, Jaillais Y. Auxin-Regulated Reversible Inhibition of TMK1 Signaling by MAKR2 Modulates the Dynamics of Root Gravitropism
Current Biology. 2020 November 5. DOI:https://doi.org/10.1016/j.cub.2020.10.011
Burr CA, Sun J, Yamburenko MV, Willoughby A, Hodgens C, Boeshore SL, Elmore A, Atkinson J, Nimchuk ZL, Bishopp A, Schaller GE, Kieber JJ. The HK5 and HK6 cytokinin receptors mediate diverse developmental pathways in rice. Development. 2020 Oct 27. doi: 10.1242/dev.191734.
Fernandez AI, Vangheluwe N, Xu K, Jourquin J, Claus LAN, Morales-Herrera S, Parizot B, De Gernier H, Yu Q, Drozdzecki A, Maruta T, Hoogewijs K, Vannecke W, Peterson B, Opdenacker D, Madder A, Nimchuk ZL, Russinova E, Beeckman T. GOLVEN peptide signaling through RGI receptors and MPK6 restricts asymmetric cell division during lateral root initiation. Nature Plants. 2020 May. doi: 10.1038/s41477-020-0645-z.
Smit M, McGregor S, Sun H, Gough C, Bågman AM, Soyars CL, Kroon JT, Gaudinier A, Williams CJ, Yang X, Nimchuk ZL, Weijers D, Turner SR, Brady SM, Etchells O. A PXY-Mediated Transcriptional Network Integrates Signaling Mechanisms to Control Vascular Development in Arabidopsis. Plant Cell 2019 December. https://doi.org/10.1105/tpc.19.00562
Worthen JM, Yamburenko MV, Lim J, Nimchuk ZL, Kieber JJ, Schaller GE. Type-B response regulators of rice play key roles in growth, development and cytokinin signaling. Development. 2019 Jul 10 . https://doi.org/10.1242/dev.174870
Rodriguez-Leal D, Xu C, Kwon CT, Soyars C, Demesa-Arevalo E, Man J, Liu L, Lemmon ZH, Jones DS, Van Eck J, Jackson DP, Bartlett ME, Nimchuk ZL, Lippman ZB. Evolution of buffering in a genetic circuit controlling plant stem cell proliferation. Nature Genetics 2019 May. https://doi.org/10.1038/s41588-019-0389-8
Vatén A, Soyars CL, Tarr PT, Nimchuk ZL, Bergmann DC. Modulation of Asymmetric Division Diversity through Cytokinin and SPEECHLESS Regulatory Interactions in the Arabidopsis Stomatal Lineage. Developmental Cell. 2018 Oct 8. https://doi.org/10.1016/j.devcel.2018.08.007
Whitewoods CD, Cammarata J, Venza ZN, Sang S, Crook AD, Aoyama T, Wang XY, Waller M, Kamisugi Y, Cuming AC, Szövényi P, Nimchuk ZL, Roeder AHK, Scanlon MJ, Harrison CJ. CLAVATA Was a Genetic Novelty for the Morphological Innovation of 3D Growth in Land Plants. Current Biology, 19 July 2018. https://doi.org/10.1016/j.cub.2018.05.068
Soyars, CL , Peterson, BA, Burr, CA, Nimchuk, ZL. Cutting Edge Genetics: CRISPR/Cas9 Editing of Plant Genomes. Plant and Cell Physiology, 18 April 2018 https://doi.org/10.1093/pcp/pcy079
Liu, H, Soyars, CL, Li, J, Fei, Q, He, G, Peterson, BA, Meyers, BC, Nimchuk, ZL, Wang, X. CRISPR/Cas9-mediated resistance to cauliflower mosaic virus. Plant Direct 2018 March 7. http://onlinelibrary.wiley.com/doi/10.1002/pld3.47
Moody, LA, Kelly, S, Coudert, Y, Nimchuk, ZL, Harrison, CJ, Langdale, JA. Somatic hybridization provides segregating populations for the identification of causative mutations in sterile mutants of the moss Physcomitrella patens. New Phytologist 2018 March 2. http://onlinelibrary.wiley.com/doi/10.1111/nph.15069
Hodgens, C, Nimchuk, ZL, Kieber, JJ. indCAPS: A tool for designing screening primers for CRISPR/Cas9 mutagenesis events. PLOS One. 2017 November 15. https://doi.org/10.1371/journal.pone.0188406
Moussu, SA, Doll, NM, Chamot, S, Brocard, L, Creff, A, Fourquin, C, Widiez, T, Nimchuk, ZL, Ingram, GC. ZHOUPI and KERBEROS Mediate Embryo/Endosperm Separation by Promoting the Formation of an Extra-Cuticular Sheath at the Embryo Surface. The Plant Cell July 2017. DOI: https://doi.org/10.1105/tpc.17.00016
Denbow CJ, Lapins S, Dietz N, Scherer R, Nimchuk ZL, Okumoto S. Gateway-compatible CRISPR-Cas9 vectors and a rapid detection by high-resolution melting curve analysis. (2017) Frontiers in Plant Sciences. https://doi.org/10.3389/fpls.2017.01171
Nimchuk, ZL, Perdue, TD. Live Imaging of Shoot Meristems on an Inverted Confocal Microscope Using an Objective Lens Inverter Attachment.
Front. Plant Sci. 2017 May 19. doi: https://doi.org/10.3389/fpls.2017.00773
Nimchuk ZL. CLAVATA1 controls distinct signaling outputs that buffer shoot stem cell proliferation through a two-step transcriptional compensation loop. PLOS Genetics. 2017 Mar 29. doi: http://dx.doi.org/10.1371/journal.pgen.1006681
Nishimura MT, Anderson RG, Cherkis KA, Law TF, Liu QL, Machius M, Nimchuk ZL, Yang L, Chung EH, El Kasmi F, Hyunh M, Osborne Nishimura E, Sondek JE, Dangl JL (2017) TIR-only protein RBA1 recognizes a pathogen effector to regulate cell death in Arabidopsis. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10) DOI: 10.1073/pnas.1620973114
Liu Y, Miao J, Traore S, Kong D, Liu Y, Zhang X, Nimchuk ZL, Liu Z, Zhao B (2016). SacB-SacR gene cassette as the negative selection marker to suppress Agrobacterium overgrowth in Agrobacterium-mediated plant transformation. Frontiers in Molecular Biosciences. 26 October 2016 http://dx.doi.org/10.3389/fmolb.2016.00070
Peterson BA, Haak DC, Nishimura MT, Teixeira PJPL, James SR, Dangl JL, Nimchuk ZL. (2016) Genome-Wide Assessment of Efficiency and Specificity in CRISPR/Cas9 Mediated Multiple Site Targeting in Arabidopsis. PLOS One 11(9): e0162169.doi:10.1371/ journal.pone.0162169.
Soyars CL, James SR, Nimchuk ZL. Ready, aim, shoot: stem cell regulation of the shoot apical meristem. Curr Opin Plant Biol. (2016) Jan 21;29:163-168. https://dx.doi.org/10.1016/j.pbi.2015.12.002
Nimchuk ZL, Zhou Y, Tarr PT, Peterson, BA, and Meyerowitz EM. Plant stem cell maintenance by transcriptional cross regulation of related receptor kinases. Development. (2015) 142: 1043-1049. https://dx.doi.org/10.1242/dev.119677
Zhou Y, Liu X, Engstrom EM, Nimchuk ZL, Pruneda-Paz J, Tarr PT, Yan A, Kay SA, Meyerowitz EM. Dual control of plant stem cell production by conserved interactions between the HAIRY MERISTEM and WUSCHEL/WUSCHEL-RELATED HOMEOBOX families of transcriptional regulators. Nature. (2015) 517:377-80. https://dx.doi.org/10.1038/nature13853
Murphy JM, Zhang Q, Young SN, Reese ML, Bailey FP, Eyers PA, Ungureanu D, Hammarén H, Silvennoinen O, Varghese LN, Chen K, Tripaydonis A, Jura N, Fukuda K, Qin J, Nimchuk Z, Mudgett MB, Elowe S, Gee CL, Liu L, Daly RJ, Manning G, Babon JJ, Lucet IS. A robust methodology to subclassify pseudokinases based on their nucleotide binding properties. Biochem J. (2014) 457, 323–334. https://dx.doi.org/10.1042/BJ20131174
Segonzac C*, Nimchuk ZL*, Beck M, Tarr PT, Robatzek S, Meyerowitz EM and Zipfel C (2011) The shoot apical meristem regulatory peptide CLV3 does not activate the immune receptor FLS2. Plant Cell 24 (8):3186-92. *Contributed equally http://dx.doi.org/10.1105/tpc.111.091264
Nimchuk ZL, Tarr PT, Meyerowitz EM. (2011). An evolutionarily conserved pseudo-kinase mediates stem cell production in plants. Plant Cell 23 (3):851-54. http://dx.doi.org/10.1105/tpc.110.075622
Nimchuk ZL, Tarr PT, Ohno C, Qu X, Meyerowitz EM. (2011). Signaling in the Arabidopsis shoot meristem stem cell niche correlates with ligand-dependent trafficking of the CLV1 receptor kinase. Current Biology 21 (5):345-52. https://dx.doi.org/10.1016%2Fj.cub.2011.01.039
Jaillais Y, Hothorn, M, Belkadir Y, Dabi T, Nimchuk ZL, Meyerowitz EM, Chory J. (2011). Tyrosine phosphorylation regulates brassinosteroid signaling at the plasma membrane. Genes and Development 25 (3):232-7. http://www.genesdev.org/cgi/doi/10.1101/gad.2001911
Previous publications on plant pathogen interactions
Ellis T*, Nimchuk Z*, Dangl JL. (2008). Arabidopsis TAO1 is a TIR-NB-LRR protein that contributes to disease resistance induced by the Pseudomonas syringae effector AvrB. PNAS 105 (17): 6475-80. *Contributed equally. https://dx.doi.org/10.1073/pnas.0802157105
Desveaux D, Singer AU, Wu A-J, McNulty BC, Musselwhite L, Nimchuk Z, Sondek J, Dangl JL. (2007). Type III effector activation via nucleotide binding, phosphorylation and host target interaction. PLOS Pathogens 3(36): e48. https://dx.doi.org/10.1371/journal.ppat.0030048
Nimchuk Z, Desveaux D, Fisher EJ, Chang JH, Dangl JL. (2007). The HopX (AvrPphE) family of Pseudomonas syringae type III effectors require a catalytic triad and a novel N-terminal domain for function. Molecular Plant Microbe Interactions 20: 346-357. https://dx.doi.org/10.1094/MPMI-20-4-0346
Belkhadir Y, Nimchuk Z, Hubert DA, Mackey D, Dangl JL. (2004) Arabidsopsis RIN4 negatively regulates RPS2 and RPM1 downstream or independent of NDR1 and is not required for AvrRpt2 or AvrRpm1 virulence functions. Plant Cell 16: 2822-35. https://dx.doi.org/10.1105/tpc.104.024117
Singer AU, Desveaux D, Betts L, Chang JH, Nimchuk Z, Grant SR, Dangl JL, Sondek J. (2004). Crystal Structure of the type III effector AvrPphF and its chaperone reveal residues required for both pathogen virulence and triggering host disease resistance. Structure 12: 1669-81. https://dx.doi.org/10.1016/j.str.2004.06.023
Nimchuk Z, Euglem T, Holt BF III, Dangl JL. (2003). Recognition and response in the plant immune system. Ann Rev Genet 37: 579-609 https://dx.doi.org/10.1146/annurev.genet.37.110801.142628
Nimchuk Z, Rohmer L, Chang JH, Dangl JL. (2001). Knowing the dancer from the dance: R-gene products and their interactions with other proteins from host and pathogen. Curr Opin Plant Biol 4: 288-94 http://dx.doi.org/10.1016/S1369-5266(00)00175-8
Nimchuk Z*, Marois E*, Kjemtrup S*, Leister RT, Katagiri F, Dangl JL. (2000). Eukaryotic fatty acylation drives plasma membrane targeting and enhances function of several type III effectors from Pseudomonas syringae. Cell 101:353-63. *Contributed equally. http://dx.doi.org/10.1016/S0092-8674(00)80846-6
Kjemtrup S, Nimchuk Z, Dangl JL. (2000). Effector proteins of phytopathogenic bacteria: bifunctional signals in virulence and host recognition. Curr Opin Microbiol 3:73-78. http://dx.doi.org/10.1016/S1369-5274(99)00054-5
Heath MC, Nimchuk ZL, Xu H. (1997). Plant nuclear migrations as indicators of critical interactions between resistant or susceptible cowpea epidermal cells and invasion hyphae of the cowpea rust fungus. New Phytol 135:689-700 http://www.jstor.org/stable/2559001